 |
|
Contingent Negative Variation and Individual Differences A New Approach in Brain Research
Joseph J. Tecce, PhD
Arch Gen Psychiatry. 1971;24(1):1-16.
Abstract
Contingent negative variation (CNV) is a slow surface-negative cortical potential in the human brain that is related to individual differences in psychological functions. Major sources of interindividual variability in CNV development among normal adults, children, and psychiatric patients involve attention and arousal functions. Consequently, a two-process theoretical model is postulated to account for individual differences in CNV, namely, that CNV amplitude is positively and monotonically related to attention functions and nonmonotonically (inverted-U) related to arousal functions. CNV also appears to be reflecting motor processes. Although CNV is a potentially useful tool in psychiatric research, eye movements can drastically alter CNV and are a serious methodological problem requiring further study. The neurophysiological genesis of CNV involves both cortical (apical dendrites in upper layers of frontal cortex) and subcortical (brain stem reticular formation) mechanisms.
Author Affiliations
Boston
From the Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston.
Footnotes
Accepted for publication July 28, 1970.
Reprint requests to Boston State Hospital, 591 Morton St, Boston 02124 (Dr. Tecce).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
The First Drink: Psychobiological Aspects of Craving
Ludwig et al.
Arch Gen Psychiatry 1974;30:539-547.
ABSTRACT
Correlations Between Averaged Evoked Potentials and Measures of Intelligence: An Overview
Callaway
Arch Gen Psychiatry 1973;29:553-558.
ABSTRACT
Contingent Negative Variation as an Indicator of Sexual Object Preference
Costell et al.
Science 1972;177:718-720.
ABSTRACT
|
