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Long-term Prognosis in Manic-Depressive IllnessA Follow-up Investigation of 111 Patients
Frank O. Shobe, MD;
Pacelli Brion, MD
Arch Gen Psychiatry. 1971;24(4):334-337.
Abstract
In a four-year period 115 manic-depressive patients were seen and subsequently followed over a period of 17.8 years. Sixty-five patients had recovered, 24 patients had improved, and 22 had not fully recovered. Several factors may be related to an unfavorable course in manic-depressive illness. More women than men did not recover. Prognosis was somewhat poorer in those patients with mania only, or both manic and depressive attacks of the illness. A history of paranoid delusions seemed to point to a poor prognosis. The prognosis in manic-depressive illness is relatively favorable.
Author Affiliations
St. Louis
From the Department of Psychiatry, Barnes & Affiliated Hospitals, St. Louis.
Footnotes
Accepted for publication Oct 6, 1970.
Reprint requests to Forty-five Hundred West Pine Clinics, 4500 W Pine Blvd, St. Louis 63108 (Dr. Shobe).
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