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Controlled Imipramine Treatment of School Phobia
Rachel Gittelman-Klein, PhD;
Donald F. Klein, MD
Arch Gen Psychiatry. 1971;25(3):204-207.
Abstract
During a double-blind, placebo-controlled study, imipramine hydrochloride was administered to 35 nonpsychotic school-phobic children. The children and their families were given a multidiscipline treatment program, concurrently with imipramine or placebo treatment. Imipramine, administered over a six-week period, was found significantly superior to placebo in inducing school return, and in global therapeutic efficacy. Doses of medication ranged from 100 to 200 mg /day. Imipramine effects could not be detected after three weeks of therapy.
Author Affiliations
Glen Oaks, NY
From the Research Department, Hillside Hospital, Glen Oaks, NY.
Footnotes
Accepted for publication Dec 21, 1970.
Reprint requests to Research Department, Hillside Hospital, 75-263rd St, Glen Oaks, NY 11004.
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