This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (111)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

I. Diagnostic Validity in Mania, Depression, and Schizophrenia

James Morrison, MD; John Clancy, MD; Raymond Crowe, MD; George Winokur, MD

Arch Gen Psychiatry. 1972;27(4):457-461.

Abstract
Five hundred twenty-five patients were selected according to specific research criteria from records of 25 to 35 years ago. Diagnoses appended to charts at that time are compared with research diagnoses. Of patients originally diagnosed as having affective disorder, 25% were discarded from research sample. Of patients originally diagnosed as schizophrenics, 63% were not included in research sample, mainly because of acute onset or episodic course. A high degree of correlation between clinical and research criteria for affective disorders was found, but criterion of "agreement amongst experienced clinicians" relatively poorly satisfies research criteria for schizophrenia.

Very stringent research diagnostic criteria were used; but for 200 schizophrenics diagnosed systematically, there was chart agreement for 95%; and in 325 affective disorders diagnosed systematically, there was 93% agreement with original chart diagnoses made in 1935.

Author Affiliations
Iowa City

From the Department of Psychiatry, University of Iowa College of Medicine, Iowa City, Iowa.

Footnotes
Accepted for publication June 2, 1972.

Reprint requests to Department of Psychiatry, University of Iowa College of Medicine, 500 Newton Rd, Iowa City, Iowa 52240 (Dr. Winokur).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Long-Term Course of Schizophrenic Illness: Bleuler's Study Reconsidered
Modestin et al.
Am. J. Psychiatry 2003;160:2202-2208.
ABSTRACT | FULL TEXT  

Selection of Controls for Family Studies: Biases and Implications
Tsuang et al.
Arch Gen Psychiatry 1988;45:1006-1008.
ABSTRACT  

An Archival Study of Depression Before and After Age 55
Wesner and Winokur
J Geriatr Psychiatry Neurol 1988;1:220-225.
ABSTRACT  

Causes of Death in DSM-III Schizophrenics and Other Psychotics (Atypical Group) A Comparison With the General Population
Buda et al.
Arch Gen Psychiatry 1988;45:283-285.
ABSTRACT  

Outcome After 40 Years in DSM-III Schizophreniform Disorder
Coryell and Tsuang
Arch Gen Psychiatry 1986;43:324-328.
ABSTRACT  

Psychiatric Illness in First-degree Relatives of Schizophrenic and Surgical Control Patients: A Family Study Using DSM-III Criteria
Kendler et al.
Arch Gen Psychiatry 1985;42:770-779.
ABSTRACT  

Mortality Studies in Psychiatry: Should They Stop or Proceed?
Tsuang and Simpson
Arch Gen Psychiatry 1985;42:98-103.
ABSTRACT  

The Chestnut Lodge Follow-up Study: I. Follow-up Methodology and Study Sample
McGlashan
Arch Gen Psychiatry 1984;41:573-585.
ABSTRACT  

Outcome of Schizophrenic Subtypes Defined by Four Diagnostic Systems
Kendler et al.
Arch Gen Psychiatry 1984;41:149-154.
ABSTRACT  

Primary Unipolar Depression and the Prognostic Importance of Delusions
Coryell and Tsuang
Arch Gen Psychiatry 1982;39:1181-1184.
ABSTRACT  

DSM-III Schizophreniformm Disorder: Comparisons With Schizophrenia and Affective Disorder
Coryell and Tsuang
Arch Gen Psychiatry 1982;39:66-69.
ABSTRACT  

Predictive Validity of DSM-III and Feighner Definitions of Schizophrenia: A Comparison With Research Diagnostic Criteria and CATEGO
Helzer et al.
Arch Gen Psychiatry 1981;38:791-797.
ABSTRACT  

Stability of Psychiatric Diagnosis: Schizophrenia and Affective Disorders Followed Up Over a 30- to 40-Year Period
Tsuang et al.
Arch Gen Psychiatry 1981;38:535-539.
ABSTRACT  

Premature Deaths in Schizophrenia and Affective Disorders: An Analysis of Survival Curves and Variables Affecting the Shortened Survival
Tsuang et al.
Arch Gen Psychiatry 1980;37:979-983.
ABSTRACT  

Long-term Outcome of Major Psychoses: I. Schizophrenia and Affective Disorders Compared With Psychiatrically Symptom-Free Surgical Conditions
Tsuang et al.
Arch Gen Psychiatry 1979;36:1295-1301.
ABSTRACT  

Excess Mortality in Schizophrenia and Affective Disorders: Do Suicides and Accidental Deaths Solely Account for This Excess?
Tsuang and Woolson
Arch Gen Psychiatry 1978;35:1181-1185.
ABSTRACT  

Suicide in Schizophrenics, Manics, Depressives, and Surgical Controls: A Comparison With General Population Suicide Mortality
Tsuang
Arch Gen Psychiatry 1978;35:153-155.
ABSTRACT  

A Study of "Atypical Schizophrenia" Comparison With Schizophrenia and Affective Disorder by Sex, Age of Admission, Precipitant, Outcome, and Family History
Tsuang et al.
Arch Gen Psychiatry 1976;33:1157-1160.
ABSTRACT  

Schizo-affective Psychosis: Fact or Fiction? A Survey of the Literature
Procci
Arch Gen Psychiatry 1976;33:1167-1178.
ABSTRACT  

Manic-Depressive Illness and Paranoid Schizophrenia: A Phenomenologic, Family History, and Treatment-Response Study
Abrams et al.
Arch Gen Psychiatry 1974;31:640-642.
ABSTRACT  

Criteria for Subtyping Schizophrenia: Clinical Differentiation of Hebephrenic and Paranoid Schizophrenia
Tsuang and Winokur
Arch Gen Psychiatry 1974;31:43-47.
ABSTRACT  

The Iowa 500: The First Follow-Up
Morrison et al.
Arch Gen Psychiatry 1973;29:678-682.
ABSTRACT  

The Iowa 500: II. A Blind Family History Comparison of Mania, Depression, and Schizophrenia
Winokur et al.
Arch Gen Psychiatry 1972;27:462-464.
ABSTRACT