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Time Production and Memory Functions

Jared R. Tinklenberg, MD; Bert S. Kopell, MD; Frederick T. Melges, MD; Leo E. Hollister, MD

Arch Gen Psychiatry. 1972;27(6):812-815.

Abstract
In a double-blind study, time production tasks and clinical tests of memory function were performed by 15 normal subjects given placebo and "social" doses of alcohol (ethyl alcohol) and marihuana, calibrated to (-)-¹-tetrahydrocannabinol. Using subjects as their own controls, it was found that, compared to alcohol and placebo, marihuana induced a significant under production of time intervals suggesting an acceleration of the internal clock. At these dose levels, there were no significant changes in memory function, but during marihuana intoxication some consistent trends toward greater impairment of tracking information over time were noted.

Author Affiliations
Palo Alto, Calif

From the departments of psychiatry and medicine, Stanford University School of Medicine and the Veterans Administration Hospital, Palo Alto, Calif.

Footnotes
Accepted for publication May 30, 1972.

Reprint requests to Palo Alto Veterans Administration Hospital, Bldg 4, Room C143, 3801 Miranda Ave, Palo Alto, Calif 94304 (Dr. Tinklenberg).

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Effects of Marihuana on Contingent Negative Variation and Reaction Time
Braden et al.
Arch Gen Psychiatry 1974;31:537-541.
ABSTRACT