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III. Selection of Treatment for Psychiatric Inpatients

John E. Overall, PhD; B.W. Henry, MD

Arch Gen Psychiatry. 1973;28(1):81-89.

Abstract
Drug treatment decisions by experienced psychiatrists in a medical school setting were examined through analysis of symptom rating profiles for patients treated with different psychotherapeutic drugs. Multidimensional analysis revealed that the several drugs scaled along a major continuum extending from antipsychotic to antidepressant indications, with antianxiety indications in the middle region. Drugs within the major chemical classes were also found to be used selectively according to clinical conceptions of the degree of tranquilizing or sedative components in their total therapeutic effects. Clinical profiles representing the indications for antidepressant, antianxiety, and antipsychotic drugs were derived.

Author Affiliations
Galveston, Tex

From the University of Texas Medical Branch, Galveston.

Footnotes
Accepted for publication May 15, 1972.

Reprint requests to Department of Neurology and Psychiatry, University of Texas Medical Branch, Galveston 77550 (Dr. Overall).

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