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Robert A. Soskin, PhD; Stainslav Grof, MD; William A. Richards, STM

Arch Gen Psychiatry. 1973;28(6):817-821.

Abstract
Dipropyltryptamine (DPT) is a hallucinogenic drug that has a shorter duration of action than lysergic acid diethylamide (LSD) and a relatively abrupt termination of activity. This study is an evaluation of the effectiveness of DPT compared to a placebo on a number of dimensions commonly regarded as significant in psychotherapy.

Eighteen alcoholic patients received a total of 72 DPT and 64 placebo therapy interviews on a double-blind basis. Doses of 15 to 30 mg of DPT were used, and the duration of the interviews was two hours. According to therapists' ratings, there was a significant enhancement in recall of memories and experiences, greater emotional expressiveness, deeper levels of self-exploration, and greater psychodynamic resolution in the DPT interviews. Patients also rated DPT sessions as more productive. These findings suggest that DPT might be a practical and useful adjunct to psychotherapy.

Author Affiliations
Baltimore

From the Maryland Psychiatric Research Center, Baltimore.

Footnotes
Accepted for publication Jan 13, 1973.

Reprint requests to Maryland Psychiatric Research Center, Box 3235, Baltimore, MD 21228 (Dr. Soskin).

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