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  Vol. 29 No. 4, October 1973 TABLE OF CONTENTS
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A Note on Twin Studies, Schizophrenia and Neurological Impairment

Edward Campion; Gary Tucker, MD

Arch Gen Psychiatry. 1973;29(4):460-464.


Abstract

Despite variations in concordance rates the fact that monozygotic twins are more often concordant for schizophrenia has been one of the major pieces of evidence supporting the genetic hypothesis of schizophrenia. While not denying the role of heredity in schizophrenia, this report concerns itself with several factors that frequently are not noted in these studies which have etiologic and methodologic implications. Specifically there are substantial physiologic and developmental differences evident in monozygotic twins which are well documented but rarely acknowledged in the existing twin studies. The role of these physiological and developmental differences may have pertinent theoretical implications for the varied findings noted in existing twin studies as well as schizophrenia in general.



Author Affiliations

Hanover, NH

From the Department of Psychiatry, Dartmouth Medical School, Hanover, NH 03755 (Dr. Tucker).


Footnotes

Accepted for publication July 3, 1973.

Reprint requests to Dartmouth Medical School, Department of Psychiatry, Hanover, NH 03755 (Dr. Tucker).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Twin Studies
Hussey
JAMA 1976;236:1734-1734.
ABSTRACT  





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