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Response to Methylphenidate in Low Socioeconomic Hyperactive Children
Stanley P. Hoffman, PhD;
David M. Engelhardt, MD;
Reuben A. Margolis, PhD;
Polizoes Polizos, MD;
Jonas Waizer, MA
Arch Gen Psychiatry. 1974;30(3):354-359.
Abstract
Sixty-two children from economically deprived urban areas and diagnosed "hyperkinetic reaction of childhood" were studied in order to evaluate the effects of methylphenidate hydrochloride in this population.
Methylphenidate was as effective in this population as it has been reported to be in children from different socioeconomic and cultural settings. Improvement was noted in many areas of the child's functioning, and was observed by the parents, the teachers, and the treating physician.
Results of the study were further analyzed by dichotomizing the children according to the weekly variability in classroom hyperactivity over the 12-week treatment period. It was found that those children whose variability in weekly ratings of classroom hyperactivity was relatively high were seen as more of a problem by their parents at the base line evaluation than were the children whose treatment response tended to be less variable.
Author Affiliations
Roberta Rosenfeld, Brooklyn, NY
From the Psychopharmacology Research Unit of the Department of Psychiatry, State University of New York, Downstate Medical Center, Brooklyn, NY.
Footnotes
Accepted for publication Sept 14, 1973.
Reprint requests to the State University of New York, Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203 (Dr. Engelhardt).
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