This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (85)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Carl Salzman, MD; Gerald E. Kochansky, PhD; Richard I. Shader, MD; Linda J. Porrino; Jerold S. Harmatz; Chester P. Swett, Jr., MD

Arch Gen Psychiatry. 1974;31(3):401-405.

Abstract
A small group model was used to examine the effects of chlordiazepoxide hydrochloride on affective and behavioral hostility in a social interactive setting. Three-person groups of male volunteers completed paper-and-pencil affective-rating scales individually and interacted with each other during a ten-minute discussion period that was videotaped and scored for behavioral hostility. The results indicated that chlordiazepoxide was associated with an increase in individual affective but not behavioral hostility. However, when a frustration stimulus was presented to the group, interpersonal behavioral hostility was increased in those who received chlordiazepoxide as compared with those taking a placebo. The data suggest that increases in hostility may be a regular rather than paradoxical effect of chlordiazepoxide. However, overt hostility may only become apparent in settings of interpersonal frustration.

Author Affiliations
From the Psychopharmacology Research Laboratory, Harvard Medical School, and the Massachusetts Mental Health Center (Drs. Salzman, Shader, and Kochansky and Mr. Harmatz); the Department of Psychology, New York University (Ms. Porrino); and the Boston Collaborative Drug Surveillance Program (Dr. Swett).

Footnotes
Accepted for publication May 14, 1974.

Reprint requests to the Psychopharmacology Research Laboratory, Massachusetts Mental Health Center, 74 Fenwood Rd, Boston, MA 02115 (Dr. Salzman).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Pharmacotherapy of Borderline Personality Disorder: Alprazolam, Carbamazepine, Trifluoperazine, and Tranylcypromine
Cowdry and Gardner
Arch Gen Psychiatry 1988;45:111-119.
ABSTRACT  

Imipramine and Chlordiazepoxide in Depressive and Anxiety Disorders: I. Efficacy in Depressed Outpatients
Lipman et al.
Arch Gen Psychiatry 1986;43:68-77.
ABSTRACT  

Differential Effects of Diazepam and Pentobarbital on Mood and Behavior
Griffiths et al.
Arch Gen Psychiatry 1983;40:865-873.
ABSTRACT  

Rage Reaction Associated with Clorazepate Dipotassium
KARCH
ANN INTERN MED 1979;91:61-62.
ABSTRACT  

Effects of Chlordiazepoxide and Oxazepam Administration on Verbal Hostility
Kochansky et al.
Arch Gen Psychiatry 1977;34:1457-1459.
ABSTRACT