 |
|
Dreaming Sleep Attacks and Desynchronized Sleep EnhancementReport of a Case of Brain Stem Signs
J. Allan Hobson, MD
Arch Gen Psychiatry. 1975;32(11):1421-1424.
Abstract
• When central neurologic signs were localized to the vestibular region of the brain stem and cerebellum, a 54-year-old man experienced frequent awakenings from nocturnal sleep and daytime sleep attacks with hallucinosis. Sleep attacks were characterized by lid fluttering and closure, upward turning of the eyes, rapid eye movements, myoclonic twitching of all extremities, and loss of consciousness, lasting one or two minutes and aborted by strong sensory stimulation. At their termination, reports of hallucinoid imagery were given.
In a sleep record of 6.5 hours, there were 2.2 hours awake (34%), 4.3 hours desynchronized sleep (66%), and a complete absence of synchronized sleep. Reports of hallucinoid imagery were given after awakenings from desynchronized sleep. The findings support the hypotheses that desynchronized sleep is normally under brain stem control and that some types of narcolepsy may be pathophysiologically related to desynchronized sleep.
Author Affiliations
From the Department of Psychiatry, Laboratory of Neurophysiology, Harvard Medical School, Boston.
Footnotes
Accepted for publication May 19, 1975.
Reprint requests to the Massachusetts Mental Health Center, 74 Fenwood Rd, Boston, MA 02115 (Dr. Hobson).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Long latency of evoked quantal transmitter release from somata of locus coeruleus neurons in rat pontine slices
Huang et al.
Proc. Natl. Acad. Sci. USA 2007;104:1401-1406.
ABSTRACT
| FULL TEXT
Transmissible Spongiform Encephalopathy (Creutzfeldt-Jakob Disease) Atypical Clinical and Pathological Findings
Schoene et al.
Arch Neurol 1981;38:473-477.
ABSTRACT
|
