You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


Advertisement

ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | RSS | Access Rights | Sign In


  Vol. 32 No. 12, December 1975 TABLE OF CONTENTS
  Online Only
 •  Online First Table of
Contents
  ORIGINAL ARTICLES
 •Online Features
 This Article
 •References
 •Full text PDF
 • Reply to article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Citing articles on Web of Science (216)
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Delicious Add to Digg Add to Facebook Add to Reddit Add to Technorati Add to Twitter What's this?

The Interictal Behavior Syndrome of Temporal Lobe Epilepsy

Stephen G. Waxman, MD, PhD; Norman Geschwind, MD

Arch Gen Psychiatry. 1975;32(12):1580-1586.


Abstract



• A distinct syndrome of interictal behavior changes occurs in many patients with temporal lobe epilepsy. These changes include alterations in sexual behavior, religiosity, and a tendency toward extensive, and in some cases compulsive, writing and drawing. The concomitants of abnormal limbic activity therefore include behavior alterations as well as manifest seizures. The demonstration of interictal spike activity in temporal structures provides a pathophysiologic basis for this syndrome. The constellation of behavioral changes may be of great diagnostic value. In addition, it provides an example of a human behavioral syndrome associated with dysfunction at specific anatomic loci. The behavior syndrome of temporal lobe epilepsy may prove to be a useful model in studies on the neural substrates for behavior.



Author Affiliations



From the Department of Neurology, Harvard Medical School, Boston, and the Neurological Unit, Boston City Hospital (Drs Waxman and Geschwind), and the Aphasia Research Center, Department of Neurology, Boston University School of Medicine (Dr Geschwind). Drs Waxman and Geschwind are now with the Neurological Unit, Beth Israel Hospital, Harvard Medical School.


Footnotes



Accepted for publication Feb 4, 1975.

Reprint requests to Neurological Unit, Beth Israel Hospital, 330 Brookline Ave, Boston, MA 02215 (Dr Waxman).



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Delicious Delicious   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

God, theologian and humble neurologist
Coles
Brain 2008;131:1953-1959.
FULL TEXT  

Anxious Bliss: A Case Study of Dissociation in a Mexican Nun
Lester
Transcultural Psychiatry 2008;45:56-78.
ABSTRACT  

Absinthe attacks
Smith
PN 2006;6:376-381.
FULL TEXT  

Detachment: gateway to the world of spirituality.
Bartocci and Dein
Transcultural Psychiatry 2005;42:545-569.
ABSTRACT  

Medicine through the novel: Lying Awake
Glannon
MH 2005;31:31-34.
ABSTRACT | FULL TEXT  

Near-Death Experiences and the Temporal Lobe
Britton and Bootzin
Psychological Science 2004;15:254-258.
ABSTRACT | FULL TEXT  

A 48-Year-Old Man With Temporal Lobe Epilepsy and Psychiatric Illness
Devinsky
JAMA 2003;290:381-392.
FULL TEXT  

The Reach of Neurology
Fisher
Arch Neurol 2003;60:173-177.
ABSTRACT | FULL TEXT  

Did Ezekiel Have Temporal Lobe Epilepsy?
Lewin Altschuler
Arch Gen Psychiatry 2002;59:561-562.
FULL TEXT  

Neural Rhythmicity, Feature Binding, and Serotonin: A Hypothesis
Fost
Neuroscientist 1999;5:79-85.
ABSTRACT  

The Case Of Anna O.: A Neuropsychiatry Perspective
Orr-Andrawes
J Am Psychoanal Assoc 1987;35:387-419.
ABSTRACT  

Cerebral Lateralization: Biological Mechanisms, Associations, and Pathology: III. A Hypothesis and a Program for Research
Geschwind and Galaburda
Arch Neurol 1985;42:634-654.
ABSTRACT  

Norman Geschwind
Damasio and Galaburda
Arch Neurol 1985;42:500-504.
 

Behavioral Symptoms in Temporal Lobe Epilepsy-Reply
Mungas
Arch Gen Psychiatry 1983;40:468-469.
ABSTRACT  

Neuroendocrine Dysfunction in Temporal Lobe Epilepsy
Herzog et al.
Arch Neurol 1982;39:133-135.
ABSTRACT  

Interictal Behavior Abnormality in Temporal Lobe Epilepsy: A Specific Syndrome or Nonspecific Psychopathology?
Mungas
Arch Gen Psychiatry 1982;39:108-111.
ABSTRACT  

Quantitative Analysis of Interictal Behavior in Temporal Lobe Epilepsy
Bear and Fedio
Arch Neurol 1977;34:454-467.
ABSTRACT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | PHYSICIAN JOBS | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1975 American Medical Association. All Rights Reserved.