This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Fetal and Neonatal Deaths

Ronald O. Rieder, MD; David Rosenthal, PhD; Paul Wender, MD

Arch Gen Psychiatry. 1975;32(2):200-211.

Abstract
This is the first report in a projected series on neurological development among the offspring of schizophrenics. An increased incidence of fetal and neonatal deaths is noted among offspring of schizophrenics when compared to a closely matched control group, using data collected prospectively.

In many cases, no apparent reason for death was determined; in some cases, major neurological malformations were found. It is necessary to consider three possible explanations for these findings—genotype of the child, adverse intrauterine environment, and medication toxicity.

Author Affiliations
Helene Blumenthal

From the Laboratory of Psychology, National Institute of Mental Health, Bethesda, Md.

Footnotes
Accepted for publication July 17, 1974.

Reprint requests to the Laboratory of Psychology, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20014 (Dr. Rieder).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Risk of stillbirth and neonatal death linked with maternal mental illness: a national cohort study
King-Hele et al.
Arch. Dis. Child. Fetal Neonatal Ed. 2009;94:F105-F110.
ABSTRACT | FULL TEXT  

Antipsychotic Therapy During Early and Late Pregnancy. A Systematic Review
Gentile
Schizophr Bull 2008;0:sbn107v1-sbn107.
ABSTRACT | FULL TEXT  

Mortality Risk Among Offspring of Psychiatric Inpatients: A Population-Based Follow-Up to Early Adulthood
Webb et al.
Am. J. Psychiatry 2006;163:2170-2177.
ABSTRACT | FULL TEXT  

Pregnancy, Delivery, and Neonatal Complications in a Population Cohort of Women With Schizophrenia and Major Affective Disorders
Jablensky et al.
Am. J. Psychiatry 2005;162:79-91.
ABSTRACT | FULL TEXT  

Structural Effects and Neurofunctional Sequelae of Developmental Exposure to Psychotherapeutic Drugs: Experimental and Clinical Aspects
Costa et al.
Pharmacol. Rev. 2004;56:103-147.
ABSTRACT | FULL TEXT  

Sudden infant death syndrome and psychiatric disorders
HOWARD and HANNAM
Br. J. Psychiatry 2003;182:379-380.
FULL TEXT  

Medical outcome of pregnancy in women with psychotic disorders and their infants in the first year after birth
HOWARD et al.
Br. J. Psychiatry 2003;182:63-67.
ABSTRACT | FULL TEXT  

Obstetric Complications and Schizophrenia: Historical and Meta-Analytic Review
Cannon et al.
Am. J. Psychiatry 2002;159:1080-1092.
ABSTRACT | FULL TEXT  

Congenital Malformations, Stillbirths, and Infant Deaths Among Children of Women With Schizophrenia
Bennedsen et al.
Arch Gen Psychiatry 2001;58:674-679.
ABSTRACT | FULL TEXT  

Dopamine-beta-hydroxylase activity and homovanillic acid in spinal fluid of schizophrenics with brain atrophy
van Kammen et al.
Science 1983;220:974-977.
ABSTRACT  

Infants at Risk for Schizophrenia: The Jerusalem Infant Development Study
Marcus et al.
Arch Gen Psychiatry 1981;38:703-713.
ABSTRACT  

Offspring of Schizophrenics III: Hyperactivity and Neurological Soft Signs
Rieder and Nichols
Arch Gen Psychiatry 1979;36:665-674.
ABSTRACT  

Neurobiologic Antecedents of Schizophrenia in Children: Evidence for an Inherited, Congenital Neurointegrative Defect
Fish
Arch Gen Psychiatry 1977;34:1297-1313.
ABSTRACT  

The Offspring of Schizophrenics: II. Perinatal Factors and IQ
Rieder et al.
Arch Gen Psychiatry 1977;34:789-799.
ABSTRACT