This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Shosuke Watanabe, MD; Hiroshi Ishino, MD; Saburo Otsuki, MD

Arch Gen Psychiatry. 1975;32(5):659-668.

Abstract
The effect of lithium carbonate therapy on patients with depression is still unconfirmed. Our past studies have shown a favorable response to the drug in patients with depression of mild or moderate severity. Therefore, we performed a controlled double-blind study of lithium carbonate and imipramine hydrochloride in 64 patients with depression.

No significant differences were noted in the overall therapeutic response, depression scale scores, or clinical effects between the two drug groups.

Author Affiliations
From the Department of Neuropsychiatry, Okayama University Medical School, Japan. Dr. Watanabe is now with the Kawasaki Medical College, Kurashiki.

Footnotes
Accepted for publication Dec 24, 1974.

Reprint requests to the Department of Neuropsychiatry, Okayama University Medical School, 2-5-1 Shikata-machi, Okayama, Japan (Dr. Otsuki).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Suicide Risk in Bipolar Disorder During Treatment With Lithium and Divalproex
Goodwin et al.
JAMA 2003;290:1467-1473.
ABSTRACT | FULL TEXT  

Practice Guideline for the Treatment of Patients With Bipolar Disorder (Revision)
Hirschfeld et al.
Focus 2003;1:64-110.
FULL TEXT  

The Addition of Lithium to Carbamazepine: Antidepressant Efficacy in Treatment-Resistant Depression
Kramlinger and Post
Arch Gen Psychiatry 1989;46:794-800.
ABSTRACT  

Lithium Carbonate Augmentation of Antidepressant Treatment: An Effective Prescription for Treatment-Refractory Depression
Heninger et al.
Arch Gen Psychiatry 1983;40:1335-1342.
ABSTRACT  

Lithium as an Antidepressant
Mendels et al.
Arch Gen Psychiatry 1979;36:845-846.
ABSTRACT  

Prediction of Tricyclic Antidepressant Response: A Critical Review
Bielski and Friedel
Arch Gen Psychiatry 1976;33:1479-1489.
ABSTRACT  

Drugs Five Years Later: Lithium Salts: 1970-1975
BALDESSARINI and LIPINSKI
ANN INTERN MED 1975;83:527-533.
ABSTRACT