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Christian Guilleminault, MD; Frederic L. Eldridge, MD; James R. Phillips, MD; William C. Dement, MD

Arch Gen Psychiatry. 1976;33(10):1241-1245.

Abstract
• Insomnia may be associated with a sleep-induced apnea syndrome in nonobese patients who snore. The "central" type of apnea appears to be predominant in this population, in opposition to Pickwickian and nonobese hypersomniacs. An abnormal "swallowing reflex syndrome," also induced by sleep, may be a differential diagnosis. Sleeping pills that are central nervous system depressants should be cautiously prescribed for patients with such syndromes.

Author Affiliations
From the Sleep Disorders Clinic and Laboratory (Drs Guilleminault and Dement) and the Department of Respiratory Medicine (Drs Eldridge and Phillips), Stanford (Calif) University School of Medicine. Dr Eldridge is now with the Physiology Department, University of North Carolina, Chapel Hill.

Footnotes
Accepted for publication Feb 4, 1975.

Reprint requests to Sleep Disorder Clinic and Laboratory, Stanford University School of Medicine, Stanford CA 94305 (Dr Guilleminault).

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