This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

An Objective Indicator in Severe Medical-Depressive Syndromes

F. Gordon Foster, MD; David J. Kupfer, MD; Patricia Coble, RN; Richard J. McPartland, MEE

Arch Gen Psychiatry. 1976;33(9):1119-1123.

Abstract
• The electroencephalographic sleep patterns of 12 patients with a final diagnosis of primary depression and those of 12 patients admitted to the Clinical Research Unit with this diagnosis, but subsequently also found to be suffering from severe medical disease, were compared. Patients with depression concurrent with severe medical disease have significantly less phasic conjugate rapid eye movement (REM) activity during REM sleep than subjects with the diagnosis of a primary depression. These findings suggest that quantification of REM density may be used clinically to distinguish between medical-depressive syndromes and primary affective disorders.

Author Affiliations
From the Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic.

Footnotes
Accepted for publication April 7, 1976.

Reprint requests to Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O'Hara St, Pittsburgh, PA 15261 (Dr Foster).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Sleep and Psychiatric Disorders: A Meta-analysis
Benca et al.
Arch Gen Psychiatry 1992;49:651-668.
ABSTRACT  

Review Article: Psychopharmacologic Treatment in Neurological Practice
Dubovsky and Ringel
Neurorehabil Neural Repair 1987;1:51-66.
 

Polysomnographic Findings in Recently Drug-Free and Clinically Remitted Depressed Patients
Rush et al.
Arch Gen Psychiatry 1986;43:878-884.
ABSTRACT  

Rapid Eye Movement Sleep Characteristics During and After Mood-Disturbing Events
Cartwright
Arch Gen Psychiatry 1983;40:197-201.
ABSTRACT  

The Sleep of Patients With Obsessive-Compulsive Disorder
Insel et al.
Arch Gen Psychiatry 1982;39:1372-1377.
ABSTRACT  

Successful Separation of Depressed, Normal, and Insomniac Subjects by EEG Sleep Data
Gillin et al.
Arch Gen Psychiatry 1979;36:85-90.
ABSTRACT