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Evidence Against Involvement of Endorphins in Sexual Arousal and Orgasm in Man
Avram Goldstein, MD;
Ralph W. Hansteen, PhD
Arch Gen Psychiatry. 1977;34(10):1179-1180.
Abstract
In a double-blind study, intravenous injection of naloxone, at a dose sufficient to saturate the opiate (endorphin) receptors, had no effect on sexual arousal, penile erection, ejaculation, or orgasm in a human subject. Apparently, endorphins are not involved in these phenomena.
Author Affiliations
From the Department of Pharmacology, Stanford University, and the Addiction Research Foundation, Palo Alto, Calif.
Footnotes
Accepted for publication Aug 4, 1977.
Reprint requests to Addiction Research Foundation, 701 Welch Rd, Palo Alto, CA 94304 (Dr Goldstein).
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