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  Vol. 34 No. 5, May 1977 TABLE OF CONTENTS
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Platelet Monoamine Oxidase in Early Childhood Autism

Donald J. Cohen, MD; J. Gerald Young, MD; Jerome A. Roth, PhD

Arch Gen Psychiatry. 1977;34(5):534-537.


Abstract



• Platelet monoamine oxidase (MAO) activity was studied in 31 individuals suffering from early childhood autism and was not significantly different from that found in normal children or adults. In the autistic children, MAO activity decreased with age, and there was a trend toward greater platelet MAO activity in prepubertal and pubertal male autistic children relative to normal male children. Total platelet counts were not elevated in autistic children.



Author Affiliations



From the Departments of Pediatrics (Drs Cohen and Young), Psychiatry (Drs Cohen and Young), Psychology (Dr Cohen), and Anesthesiology (Dr Roth), Yale University School of Medicine, and the Child Study Center, New Haven, Conn. Dr Roth is now with the Department of Pharmacology and Therapeutics, School of Medicine and Dentistry, State University of New York at Buffalo.


Footnotes



Accepted for publication March 17, 1976.

Reprint requests to Yale Child Study Center, 333 Cedar St, New Haven, CT 06510 (Dr Cohen).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Dopamine and Serotonin Metabolism in Neuropsychiatrically Disturbed Children: CSF Homovanillic Acid and 5-Hydroxyindoleacetic Acid
Cohen et al.
Arch Gen Psychiatry 1977;34:545-550.
ABSTRACT  





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