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Emergence According to Benztropine Prophylaxis

Chester Swett, Jr, MD; Jonathan O. Cole, MD; Samuel Shapiro, MD; Dennis Slone, MD

Arch Gen Psychiatry. 1977;34(8):942-943.

Abstract
• The frequency of extrapyramidal symptoms (EPS) attributed to chlorpromazine among 86 patients who received benztropine for the prevention of EPS (9.3%) was similar to that of the 568 patients who received chlorpromazine alone (10.6%). The data in this small sample indicated that the prophylactic use of benztropine had no effect in reducing the rate of EPS.

Author Affiliations
From the Drug Epidemiology Unit, Boston University Medical Center.

Footnotes
Accepted for publication July 7, 1976.

Reprint requests to McLean Hospital, 115 Mill St, Belmont, MA 02178 (Dr Swett).

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ABSTRACT