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An Affective Disorder?

Dennis P. Cantwell, MD; Susan Sturzenberger, PhD; Jane Burroughs, MSW; Barbara Salkin, MSW; Jacquelyn K. Green, MD

Arch Gen Psychiatry. 1977;34(9):1087-1093.

Abstract
• Follow-up data on 26 patients hospitalized during adolescence for anorexia nervosa are presented. The mean length of follow-up was 4.9 years. There were no mortalities. Only one patient at the time of follow-up was still possibly anorexic. However, a substantial number of the patients did have other eating difficulties. Most striking was the clinical psychopathology present at follow-up, particularly the incidence of affective disorder. A large number of the patients manifested depressive symptomatology in both the premorbid and the postmorbid states, as well as at the time of follow-up. A family history of affective disorder was particularly common in the mothers of the anorexic patients. Data from this study are consistent with the hypothesis that there is a strong relationship between anorexia nervosa and affective disorder.

Author Affiliations
From the Neuropsychiatric Institute, University of California, Los Angeles.

Footnotes
Accepted for publication Nov 15, 1976.

Reprints not available.

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