This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (95)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

John R. Brinkley, MD; Bernard D. Beitman, MD; Robert O. Friedel, MD

Arch Gen Psychiatry. 1979;36(3):319-326.

Abstract
• The use of pharmacologic agents in treating patients described as borderline generally has been accorded an insignificant, or at best, minor, role. We discuss this observation and review the literature that has dealt with this aspect of treatment. Diagnostic criteria are presented that appear to define a specific population of borderline patients who have been observed to be responsive to low doses of neuroleptic drugs. Five case histories of patients with conditions diagnosed and treated in this manner are presented, followed by a discussion of the implications of this approach in terms of clarifying the nosologic issues that have arisen around the "borderline" concept.

Author Affiliations
From the Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle (Drs Brinkley and Beitman) and the Department of Psychiatry, Medical College of Virginia, Richmond (Dr Friedel).

Footnotes
Accepted for publication Feb 24, 1978.

Reprint requests to Harborview Community Mental Health Center, 326 Ninth Ave, Seattle, WA 98104 (Dr Brinkley).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Drug treatment for personality disorders
Tyrer and Bateman
Adv. Psychiatr. Treat. 2004;10:389-398.
ABSTRACT | FULL TEXT  

Electrophysiological Aberrations in Borderline Personality Disorder: State of the Evidence
Boutros et al.
J. Neuropsychiatry Clin. Neurosi. 2003;15:145-154.
ABSTRACT | FULL TEXT  

Auditory P300 in Borderline Personality Disorder and Schizophrenia
Kutcher et al.
Arch Gen Psychiatry 1987;44:645-650.
ABSTRACT  

Borderline and Schizotypal Personality Disorders Treated With Low-Dose Thiothixene vs Placebo
Goldberg et al.
Arch Gen Psychiatry 1986;43:680-686.
ABSTRACT  

Progress in Pharmacotherapy of Borderline Disorders: A Double-blind Study of Amitriptyline, Haloperidol, and Placebo
Soloff et al.
Arch Gen Psychiatry 1986;43:691-697.
ABSTRACT  

Pharmacotherapy for Patients With Borderline Personality Disorder
Gunderson
Arch Gen Psychiatry 1986;43:698-700.
ABSTRACT  

Borderline Personality Disorder: Construct Validity of the Concept
Kroll et al.
Arch Gen Psychiatry 1981;38:1021-1026.
ABSTRACT  

Psychiatry
Freedman
JAMA 1980;243:2208-2210.
ABSTRACT