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A Controlled Prospective Ten-Year Follow-up of 75 Children

Gabrielle Weiss, MD; Lily Hechtman, MD; Terrye Perlman, MEd; Joyce Hopkins, MA; Albert Wener, PhD

Arch Gen Psychiatry. 1979;36(6):675-681.

Abstract
• This study reports on a variety of outcome variables from 75 hyperactive and 44 matched control subjects aged 17 to 24 years (mean ages, 19.5 and 19.0 years, respectively).

All hyperactive subjects have been followed up for 10 to 12 years; they were first evaluated at 6 to 12 years of age. None of the hyperactive subjects was treated with methylphenidate, although a subgroup received chlorpromazine or a mixture of drugs (excluding methylphenidate). The hyperactive subjects had less education than the controls and a history of more car accidents and more geographical moves. However, only a minority were still engaged in continued antisocial behavior or had evidence of severe psychopathology. No subjects were found to be psychotic, but two were diagnosed as borderline psychotic. There was evidence that hyperactive subjects had some continued symptoms from the hyperkinetic child syndrome, including impulsive personality traits.

Author Affiliations
From the Departments of Psychiatry (Drs Weiss and Hechtman and Ms Perlman) and Psychology (Ms Hopkins and Dr Wener), Montreal Children's Hospital, and the Department of Psychiatry, McGill University, Montreal (Drs Weiss and Hechtman). Ms Hopkins is now with the Department of Psychology, University of Pittsburgh.

Footnotes
Accepted for publication Sept 5, 1978.

Read in part before the Canadian Psychiatric Association, Quebec, Sept 28-Oct 2, 1976.

Reprint requests to Department of Psychiatry, Montreal Children's Hospital, 2300 Tupper St, Montreal, Quebec H3H 1P3, Canada (Dr Weiss).

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