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Lithium Transport Across the RBC MembraneA Study of Genetic Factors
Elizabeth Dorus, PhD;
Ghanshyam N. Pandey, PhD;
Rita Shaughnessy, PhD;
John M. Davis, MD
Arch Gen Psychiatry. 1980;37(1):80-81.
Abstract
The measurement of the ratio of RBC to plasma lithium ion levels in vitro in 291 members of 120 families indicated that genetic factors contribute substantially to interindividual variability in the lithium ion distribution across the RBC membrane. These factors affect the lithium-sodium ion exchange system that determines the lithium ion distribution.
Arch Gen Psychiatry 37:80-81,1980)
Author Affiliations
From the Department of Psychiatry, University of Chicago (Drs Dorus, Pandey, and Davis); and the Department of Research, Illinois State Psychiatric Institute, Chicago (Drs Pandey, Shaughnessy, and Davis).
Footnotes
Accepted for publication June 29, 1979.
Reprint requests to Department of Psychiatry, University of Chicago, 950 E 59th St, Chicago, IL 60637 (Dr Dorus).
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