This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Richard J. Haier, PhD; Monte S. Buchsbaum, MD; Dennis L. Murphy, MD; Irving I. Gottesman, PhD; Robert D. Coursey, PhD

Arch Gen Psychiatry. 1980;37(3):340-345.

Abstract
• College students in two separate studies had platelet monoamine oxidase (MAO) activity determinations and average evoked potential (AEP) measurements taken. On the basis of Minnesota Multiphasic Personality Inventory (MMPI) or Research Diagnostic Criteria (RDC) evaluations, psychopathology, particularly affective disorder, was found to be more prevalent among both persons with the combination of low MAO activity and AEP augmenting and those with high MAO activity and AEP reducing. The same pattern is apparent whether students were selected for extremely high or low MAO activity (study 1) or for elevated or normal MMPI scores (study 2). Some psychiatric patient groups also show this pattern. An interactive model of sensation-seeking and sensory inhibition is presented.

Author Affiliations
From the Laboratory of Psychology and Psychopathology (Dr Haier), Biological Psychiatry Branch (Dr Buchsbaum), and the Clinical Neuropharmacology Branch (Dr Murphy), National Institute of Mental Health, Bethesda, Md, the Psychology Department, University of Minnesota, Minneapolis (Dr Gottesman), and the Psychology Department, University of Maryland, College Park (Dr Coursey). Dr Haier is presently with Butler Hospital, Providence, RI.

Footnotes
Accepted for publication March 30, 1979.

Reprint requests to Butler Hospital, 345 Blackstone Blvd, Providence, RI 02906 (Dr Haier).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Monoamine Oxidase and Criminality: Identifying an Apparent Biological Marker for Antisocial Behavior
ELLIS
Journal of Research in Crime and Delinquency 1991;28:227-251.
ABSTRACT  

Attention Dysfunction and Psychopathology in College Men
Buchsbaum et al.
Arch Gen Psychiatry 1985;42:354-360.
ABSTRACT  

Sex and Group Differences in Reading and Attention Disordered Children with and without Hyperkinesis
Ackerman et al.
J Learn Disabil 1983;16:407-415.
ABSTRACT  

Smooth Pursuit Eye Tracking Impairment: Relation to Other 'Markers' of Schizophrenia and Psychologic Correlates
Siever et al.
Arch Gen Psychiatry 1982;39:1001-1005.
ABSTRACT