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Schizophrenia-Primary Affective Disorder DiscriminationI. Development of a Data-Based Diagnostic Index
Richard C. Fowler, MD;
Barry I. Liskow, MD;
Vasantkumar L. Tanna, MD;
Linda Lytle, MSW;
Juan Mezzich, MD, PhD
Arch Gen Psychiatry. 1980;37(7):811-814.
Abstract
A nine-variable diagnostic measure for discriminating schizophrenia and primary affective disorder was developed. The nine variables, which were selected by discriminant function analysis, reflect past and current symptomatology, duration of symptoms, and behavioral ratings. The measure was crossvalidated by a jackknife procedure that accurately classified nine of ten of the cases. Such accuracy suggests that brief, databased diagnostic instruments have considerable promise as practical checks of clinical diagnoses.
Author Affiliations
From the Veterans Administration Medical Center and the University of California School of Medicine, San Diego (Dr Fowler); the Veterans Administration Hospital and the University of Iowa College of Medicine, Iowa City (Drs Liskow and Tanna and Ms Lytle); and the University of Pittsburgh School of Medicine, Pittsburgh (Dr Mezzich).
Footnotes
Accepted for publication Jan 30, 1980.
Reprint requests to Veterans Administration Medical Center (116A), 3350 La Jolla Village Dr, San Diego, CA 92161 (Dr Fowler).
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