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Herbert Weingartner, PhD; Robert M. Cohen, MD, PhD; Dennis L. Murphy, MD; John Martello, MA; Cheryl Gerdt, BA

Arch Gen Psychiatry. 1981;38(1):42-47.

Abstract
• During depressive episodes, patients show both qualitative and quantitative changes in how information is processed. Depressed patients appear to use weak or incomplete encoding strategies to organize and transform events to be remembered. This makes these events less memorable. If the depressed patient is provided organization and structure, then learningmemory deficits are not apparent. Disruptions in arousal-activation in depression can account for these cognitive impairments.

Author Affiliations
From the National Institute of Mental Health, Bethesda, Md.

Footnotes
Accepted for publication Dec 6, 1979.

Reprint requests to Laboratory of Psychology and Psychopathology, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20205 (Dr Weingartner).

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