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Effects of Artificial Food Colorings in Children With Hyperactive SymptomsA Critical Review and Results of a Controlled Study
Jeffrey A. Mattes, MD;
Rachel Gittelman, PhD
Arch Gen Psychiatry. 1981;38(6):714-718.
Abstract
The "Feingold diet," which eliminates artificial food colorings, has been claimed to be beneficial to hyperactive children. Previous studies have yielded equivocal results. We sought to maximize the likelihood of demonstrating behavioral effects of artificial food colorings by (1) studying only children who were already on the Feingold diet and who were reported by their parents to respond markedly to artificial food colorings, (2) attempting to exclude placebo responders, and (3) administering high dosages of coloring. The design was a double-blind crossover with order randomized; 11 children maintained on the Feingold diet were challenged with food coloring and placebo (one each week). Evaluations by parents, teachers, and psychiatrists and psychological testing yielded no evidence of a food coloring effect.
Author Affiliations
From Long Island Jewish-Hillside Medical Center, Glen Oaks, NY (Dr Mattes); and the Department of Psychology, New York State Psychiatric Institute and Columbia-Presbyterian Medical Center, New York (Dr Gittelman). Dr Mattes is now with the Veterans Administration Medical Center, Bronx, NY.
Footnotes
Accepted for publication Jan 22, 1981.
Read in part before the annual meeting of the American Psychiatric Association, San Francisco, May 7, 1980.
Reprint requests to Veterans Administration Medical Center, 130 W Kingsbridge Rd, Bronx, NY 10468 (Dr Mattes).
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