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Angela Knights, MB, MRCPsych; Steven R. Hirsch, MD, MPhil, MRCP, FRCPsych

Arch Gen Psychiatry. 1981;38(7):806-811.

Abstract
• Symptoms of depression are common in patients who have been treated for schizophrenia. Various concepts have been proposed to explain the relationship between depression and schizophrenia. Data for schizophrenic patients in prospective studies and a comparison group of depressives show that depressive symptoms are more prevalent during the acute phase of the illness and that they decrease (rather than increase) in severity with effective neuroleptic treatment.

Author Affiliations
From the Department of Psychiatry, Charing Cross Hospital Medical School, London. Dr Knights is now at Carlton Hayes Hospital, Leicester, England.

Footnotes
Accepted for publication Jan 22, 1981.

Reprint requests to Department of Psychiatry, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, England (Prof Hirsch).

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