This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

III. The Relationship Between Paranoid Psychosis (Delusional Disorder) and the Schizophrenia Spectrum Disorders

Kenneth S. Kendler, MD; Alan M. Gruenberg, MD; John S. Strauss, MD

Arch Gen Psychiatry. 1981;38(9):985-987.

Abstract
• The genetic relationship between paranoid psychosis (delusional disorder) and schizophrenia spectrum disorders (schizophrenia and schizotypal personality disorder) is examined by a blind independent diagnostic evaluation of the interviews of relatives from the greater Copenhagen sample of the Danish Adoption Study of Schizophrenia. While cases of schizophrenia spectrum disorders are strongly concentrated in the biologic relatives of the schizophrenic adoptees, this pattern is not found for delusional disorder. These results suggest that from a genetic perspective, delusional disorder is not part of the schizophrenia spectrum.

Author Affiliations
From the Department of Psychiatry and the Schizophrenia Biological Research Center, Bronx Veterans Administration Medical Center, Mt Sinai School of Medicine, Bronx, NY (Dr Kendler); the Connecticut Mental Health Center, New Haven (Dr Gruenberg); and the Department of Psychiatry, Yale University School of Medicine, New Haven, Conn (Drs Gruenberg and Strauss).

Footnotes
Accepted for publication April 20, 1981.

Reprint requests to Department of Psychiatry, Bronx VA Medical Center, 130 W Kingsbridge Rd, Bronx, NY 10468 (Dr Kendler).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Genetic Boundaries of the Schizophrenia Spectrum: Evidence From the Finnish Adoptive Family Study of Schizophrenia
Tienari et al.
Am. J. Psychiatry 2003;160:1587-1594.
ABSTRACT | FULL TEXT  

Independent Diagnoses of Adoptees and Relatives As Defined by DSM-III in the Provincial and National Samples of the Danish Adoption Study of Schizophrenia
Kendler et al.
Arch Gen Psychiatry 1994;51:456-468.
ABSTRACT  

Psychiatric Illness in First-degree Relatives of Schizophrenic and Surgical Control Patients: A Family Study Using DSM-III Criteria
Kendler et al.
Arch Gen Psychiatry 1985;42:770-779.
ABSTRACT  

An Independent Analysis of the Danish Adoption Study of Schizophrenia: VI. The Relationship Between Psychiatric Disorders as Defined by DSM-III in the Relatives and Adoptees
Kendler and Gruenberg
Arch Gen Psychiatry 1984;41:555-564.
ABSTRACT  

Demography of Paranoid Psychosis (Delusional Disorder) A Review and Comparison With Schizophrenia and Affective Illness
Kendler
Arch Gen Psychiatry 1982;39:890-902.
ABSTRACT