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Smadar Levin, PhD; Ashby Jones, OD, MS; Lawrence Stark, MD; Edward L. Merrin, MD; Philip S. Holzman, PhD

Arch Gen Psychiatry. 1982;39(10):1125-1130.

Abstract
• Using precise infrared recording instrumentation, we measured the eye-movement patterns in six schizophrenic patients who were taking medication and found saccadic intrusions and saccadic smooth-pursuit tracking in three. This defined some of the eye-movement irregularities reported previously by many investigators. A variety of eye-movement functions in addition to smooth pursuit exhibited these abnormalities, including fixation, vergence, and head-eye pursuit. Saccadic intrusions or saccadic pursuit also occurs in a number of neuro-ophthalmologic disorders, and occasionally In healthy normal subjects. Thus, these eye-movement abnormalities do not occur exclusively in schizophrenia.

Author Affiliations
From the Department of Physiological Optics, Neurology Laboratory, University of California, Berkeley (Drs Levin, Jones, and Stark); the Department of Psychiatry, University of California, San Francisco School of Medicine and the Veterans Administration Medical Center, San Francisco (Dr Merrin); and the Department of Psychology and Social Relations, Harvard University, Cambridge, Mass, and the Mailman Research Center, McLean Hospital, Belmont, Mass (Drs Levin and Holzman).

Footnotes
Accepted for publication March 30, 1982.

Reprint requests to Mailman Research Center, McLean Hospital, 115 Mill St, Belmont, MA 02178 (Dr Levin).

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