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II. Is It a Variant of Schizophrenia or Affective Disorder?

Thomas H. McGlashan, MD

Arch Gen Psychiatry. 1983;40(12):1319-1323.

Abstract
• Recent studies question whether the borderline syndrome represents two entities: borderline schizophrenia (or schizotypal personality) as a variant of schizophrenia and borderline personality disorder as a variant of primary affective disorder. Relevant data are presented from the long-term follow-up of patients at the Chestnut Lodge, Rockville, Md, receiving systematic diagnoses by the retrospective application of diagnostic criteria. Studied were (1) diagnostic overlap at index admission, (2) diagnostic change over follow-up period, and (3) comparative long-term functional outcome between borderline samples and other diagnostic groups. Findings supported the hypothesis that schizotypal personality (as defined by DSM-III) is a variant of schizophrenia but borderline personality disorder (as defined by the DSM-III and Gunderson et al criteria) is not. An affiliation of borderline personality disorder with primary affective disorder is suggested although not conclusive.

Author Affiliations
From the Chestnut Lodge Research Institute, Rockville, Md.

Footnotes
Accepted for publication April 8, 1983.

Read before the annual meeting of the American Psychiatric Association, New York, May 3, 1983.

Reprint requests to Chestnut Lodge Research Institute, 500 W Montgomery Ave, Rockville, MD 20850 (Dr McGlashan).

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