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  Vol. 41 No. 5, May 1984 TABLE OF CONTENTS
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Lymphocyte Function in Major Depressive Disorder

Steven J. Schleifer, MD; Steven E. Keller, PhD; Arthur T. Meyerson, MD; Marjorie J. Raskin, MD; Kenneth L. Davis, MD; Marvin Stein, MD

Arch Gen Psychiatry. 1984;41(5):484-486.


Abstract



Lymphocyte stimulation by phytohemagglutinin, concanavalin A, and pokeweed mitogen was significantly lower in a group of hospitalized depressed patients than in matched controls. The absolute number of T and B cells was lower in the depressed group, but the percentage of these cell types did not differ between the groups. These findings may be related to the altered neuroendocrine function found in patients with depressive disorders.



Author Affiliations



From the Howard Mack Laboratory, Department of Psychiatry, Mount Sinai School of Medicine of the City University of New York.


Footnotes



Accepted for publication Sept 22, 1983.

Reprint requests to Department of Psychiatry, Mount Sinai School of Medicine, 1 Gustave L. Levy Pl, New York, NY 10029 (Dr Schleifer).



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