This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Steven J. Schleifer, MD; Steven E. Keller, PhD; Arthur T. Meyerson, MD; Marjorie J. Raskin, MD; Kenneth L. Davis, MD; Marvin Stein, MD

Arch Gen Psychiatry. 1984;41(5):484-486.

Abstract
Lymphocyte stimulation by phytohemagglutinin, concanavalin A, and pokeweed mitogen was significantly lower in a group of hospitalized depressed patients than in matched controls. The absolute number of T and B cells was lower in the depressed group, but the percentage of these cell types did not differ between the groups. These findings may be related to the altered neuroendocrine function found in patients with depressive disorders.

Author Affiliations
From the Howard Mack Laboratory, Department of Psychiatry, Mount Sinai School of Medicine of the City University of New York.

Footnotes
Accepted for publication Sept 22, 1983.

Reprint requests to Department of Psychiatry, Mount Sinai School of Medicine, 1 Gustave L. Levy Pl, New York, NY 10029 (Dr Schleifer).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

What's "Unstable" in Unstable Angina?
Ketterer et al.
Psychosomatics 2004;45:185-196.
ABSTRACT | FULL TEXT  

Reduced Primary Antibody Responses in a Genetic Animal Model of Depression
Friedman et al.
Psychosom. Med. 2002;64:267-273.
ABSTRACT | FULL TEXT  

Pathways Linking Major Depression and Immunity in Ambulatory Female Patients
Miller et al.
Psychosom. Med. 1999;61:850-860.
ABSTRACT | FULL TEXT  

Depression in Patients With Cancer: Diagnosis, Biology, and Treatment
McDaniel et al.
Arch Gen Psychiatry 1995;52:89-99.
ABSTRACT  

Environmental exposures: psychological stress
Fahey
Hum Exp Toxicol 1995;14:92-94.
 

The effects of chronic lithium chloride administration on some behavioural and immunological changes in the bilaterally olfactory bulbectomized rat
Cai Song and Leonard
J Psychopharmacol 1994;8:40-47.
ABSTRACT  

Circulating Natural Killer Cell Phenotypes in Men and Women With Major Depression: Relation to Cytotoxic Activity and Severity of Depression
Evans et al.
Arch Gen Psychiatry 1992;49:388-395.
ABSTRACT  

Depression, the Immune System, and Health and Illness: Findings in Search of Meaning
Stein et al.
Arch Gen Psychiatry 1991;48:171-177.
ABSTRACT  

Psychological Stress--Induced Modulation of Interleukin 2 Receptor Gene Expression and Interleukin 2 Production in Peripheral Blood Leukocytes
Glaser et al.
Arch Gen Psychiatry 1990;47:707-712.
ABSTRACT  

Major Depressive Disorder, Alcoholism, and Reduced Natural Killer Cell Cytotoxicity: Role of Severity of Depressive Symptoms and Alcohol Consumption
Irwin et al.
Arch Gen Psychiatry 1990;47:713-719.
ABSTRACT  

A Structured Psychiatric Intervention for Cancer Patients: II. Changes Over Time in Immunological Measures
Fawzy et al.
Arch Gen Psychiatry 1990;47:729-735.
ABSTRACT  

Chronic Fatigue: A Prospective Clinical and Virologic Study
Gold et al.
JAMA 1990;264:48-53.
ABSTRACT  

The Nature and Course of Depression Following Myocardial Infarction
Schleifer and Macari-Hinson
Arch Intern Med 1989;149:1785-1789.
ABSTRACT  

Major Depressive Disorder and Immunity: Role of Age, Sex, Severity, and Hospitalization
Schleifer et al.
Arch Gen Psychiatry 1989;46:81-87.
ABSTRACT  

Blunted {beta}-Adrenergic Responsivity of Peripheral Blood Mononuclear Cells in Endogenous Depression: Isoproterenol Dose--Response Studies
Halper et al.
Arch Gen Psychiatry 1988;45:241-244.
ABSTRACT  

Neurobiology of Seasonal Affective Disorder and Phototherapy
Skwerer et al.
J Biol Rhythms 1988;3:135-154.
 

Metabolic Stress Produces Rapid Immunosuppression in Humans
Breier et al.
Arch Gen Psychiatry 1987;44:1108-1109.
ABSTRACT  

Affective Disorder and Viral Infections-Reply
DeLisi et al.
Arch Gen Psychiatry 1987;44:760-760.
ABSTRACT  

Borna Disease Virus: A Possible Etiologic Factor in Human Affective Disorders?
Amsterdam et al.
Arch Gen Psychiatry 1985;42:1093-1096.
ABSTRACT  

Depression and Immunity: Lymphocyte Function in Ambulatory Depressed Patients, Hospitalized Schizophrenic Patients, and Patients Hospitalized for Herniorrhaphy
Schleifer et al.
Arch Gen Psychiatry 1985;42:129-133.
ABSTRACT