Subjective Responses to Alcohol in Sons of Alcoholics and Control Subjects

doi:10.1001/archpsyc.1984.01790200061008

You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.

Vol. 41 No. 9, September 1984

Online Only
	•	Online First Table of Contents

ORIGINAL ARTICLES

•	Online Features

This Article
•	References
•	Full text PDF
•	Reply to article
•	Send to a friend
•	Save in My Folder
•	Save to citation manager
•	Permissions

Citing Articles
•	Citation map
•	Citing articles on HighWire
•	Citing articles on Web of Science (265)
•	Contact me when this article is cited

Related Content
•	Similar articles in this journal

Social Bookmarking
	What's this?

Subjective Responses to Alcohol in Sons of Alcoholics and Control Subjects

Marc A. Schuckit, MD

Arch Gen Psychiatry. 1984;41(9):879-884.

Abstract

• We matched 23 nonalcoholic male drinkers who were aged21 to 25 years and had alcoholic close relatives (FHP) with23 control subjects with negative family histories (FHN) fordemographic characteristics and drinking and smoking histories.The subjective feelings of intoxication for the 46 men werestudied on three occasions using placebo, 0.75 mL/kg of ethanol,and 1.1 mL/kg of ethanol. The FHP subjects (at elevated riskfor the development of alcoholism) reported less intense feelingsof subjective intoxication after drinking, especially duringthe two hours following the peak blood alcohol concentration(BAC). Group differences were most marked with the 0.75-mL/kgdose. The two groups did not differ significantly on their BACsnor on the expectation of how they would feel under the influenceof alcohol.

Author Affiliations

From the Department of Psychiatry, University of California School of Medicine, San Diego, and the Alcoholism Treatment Program, San Diego Veterans Administration Medical Center.

Footnotes

Accepted for publication Dec 28, 1983.

Reprint requests to Veterans Administration Hospital, 3350 LaJolla Village Dr, San Diego, CA 92161 (Dr Schuckit).

Add to CiteULike CiteULike Add to Connotea Connotea Add to Delicious Delicious Add to Digg Digg Facebook Add to Reddit Reddit Add to Technorati Technorati Twitter What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Experimental medicine in drug addiction: towards behavioral, cognitive and neurobiological biomarkers
Duka et al.
J Psychopharmacol 2011;25:1235-1255.
ABSTRACT | FULL TEXT

Rewarding, Stimulant, and Sedative Alcohol Responses and Relationship to Future Binge Drinking
King et al.
Arch Gen Psychiatry 2011;68:389-399.
ABSTRACT | FULL TEXT

Effects of Naltrexone on Alcohol Sensitivity and Genetic Moderators of Medication Response: A Double-blind Placebo-Controlled Study
Ray and Hutchison
Arch Gen Psychiatry 2007;64:1069-1077.
ABSTRACT | FULL TEXT

Early Reactions to Cannabis Predict Later Dependence
Fergusson et al.
Arch Gen Psychiatry 2003;60:1033-1039.
ABSTRACT | FULL TEXT

Common Quantitative Trait Loci for Alcohol-Related Behaviors and Central Nervous System Neurotensin Measures: Hypnotic and Hypothermic Effects
Erwin et al.
J. Pharmacol. Exp. Ther. 1997;280:911-918.
ABSTRACT | FULL TEXT

The Clinical Significance of the Thyrotropin-Releasing Hormone Test in Alcoholic Men
Sellman and Joyce
Aust N Z J Psychiatry 1992;26:577-585.
ABSTRACT

A Simultaneous Evaluation of Multiple Markers of Ethanol/Placebo Challenges in Sons of Alcoholics and Controls
Schuckit and Gold
Arch Gen Psychiatry 1988;45:211-216.
ABSTRACT

Plasma Cortisol Levels Following Ethanol in Sons of Alcoholics and Controls
Schuckit et al.
Arch Gen Psychiatry 1987;44:942-945.
ABSTRACT

Genetics and the Risk for Alcoholism
Schuckit
JAMA 1985;254:2614-2617.
ABSTRACT

Ethanol-Induced Changes in Body Sway in Men at High Alcoholism Risk
Schuckit
Arch Gen Psychiatry 1985;42:375-379.
ABSTRACT

| | |