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Michie N. Hesselbrock, PhD; Roger E. Meyer, MD; Janet J. Keener

Arch Gen Psychiatry. 1985;42(11):1050-1055.

Abstract
• This study utilized the DSM-III criteria and the National Institute of Mental Health Diagnostic Interview Schedule to assess the prevalence of lifetime psychopathology among hospitalized alcoholics. Antisocial personality (ASP) and substance-use disorder were common psychopathologies among male alcoholics and major depression and phobia were common among female alcoholics. The onset of most psychopathologies preceded the abuse of alcohol among women. In men, however, with the exception of ASP and panic disorder, the onset of psycopathology was subsequent to that of alcohol abuse and/or dependence. Diagnoses of ASP and substance abuse were characterized by early onset of regular intoxication and alcohol abuse. Gender and the presence of specific psychopathology appeared to modify the course and symptom picture of alcoholism. In general, alcoholic women showed a later onset of regular intoxication and a more rapid progression to alcohol abuse and dependence than alcoholic men.

Author Affiliations
From the Alcohol Research Center, Department of Psychiatry, University of Connecticut Health Center, Farmington.

Footnotes
Accepted for publication May 18, 1984.

Reprint requests to Department of Psychiatry, University of Connecticut Health Center, Farmington, CT 06032 (Dr Hesselbrock).

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