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Robert M. A. Hirschfeld, MD; Gerald L. Klerman, MD; Nancy C. Andreasen, MD, PhD; Paula J. Clayton, MD; Martin B. Keller, MD

Arch Gen Psychiatry. 1985;42(11):1109-1114.

Abstract
• Fifty-seven patients with situational major depression diagnosed by the Research Diagnostic Criteria were compared with 72 subjects with nonsituational major depression on demographic, clinical, and psychosocial variables. The situational patients tended to be younger and had fewer prior episodes of depression and fewer hospitalizations. No differences were found in categories of life events, in overall clinical picture, in social supports, or in family history.

Author Affiliations
From the Center for Studies of Affective Disorders, Clinical Research Branch, National Institute of Mental Health, Rockville, Md (Dr Hirschfeld); the Department of Psychiatry, Harvard Medical School and Massachusetts General Hospital, Boston (Drs Klerman and Keller); the Department of Psychiatry, College of Medicine, University of Iowa, Iowa City (Dr Andreasen); and the Department of Psychiatry, University of Minnesota, University Hospital, Minneapolis (Dr Clayton).

Footnotes
Accepted for publication March 27, 1985.

Reprint requests to Department of Health and Human Services, Alcohol, Drug Abuse, and Mental Health Administration, National Institute of Mental Health, Rockville, MD 20857 (Dr Hirschfeld).

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