This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (84)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

New Data and Reappraisal

George Winokur, MD

Arch Gen Psychiatry. 1985;42(11):1116-1122.

Abstract
• A family history of alcoholism can be used as a validating factor in the diagnosis of reactive-neurotic depression. Not only is this true but there are clear data that indicate the presence of positive symptoms that can be used to make the diagnosis. A set of criteria based on previous research is presented for the diagnosis of neurotic-reactive depression. These criteria are based on a clustering of certain symptoms, events, and traits in patients with neurotic-reactive depression. The patients showed stormy life-styles, some specific symptoms, personality abnormalities, presence of life events before the onset of depression, and a family history of alcoholism. They had relatively few hospitalizations for depression and responded poorly to specific antidepressant treatment.

Author Affiliations
From the Department of Psychiatry, University of Iowa College of Medicine, Iowa City.

Footnotes
Accepted for publication Jan 7, 1985.

Reprint requests to University of Iowa Hospitals and Clinics, Department of Psychiatry, 500 Newton Rd, Iowa City, IA 52242 (Dr Winokur).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Psychiatric illness in the first-degree relatives of persons reporting multiple chemical sensitivities
Black et al.
Toxicol Ind Health 1999;15:410-414.
ABSTRACT  

The Identification and Validation of Distinct Depressive Syndromes in a Population-Based Sample of Female Twins
Kendler et al.
Arch Gen Psychiatry 1996;53:391-399.
ABSTRACT  

Detoxified alcoholics, major depressives and tyramine sulphate excretion
Hale et al.
J Psychopharmacol 1995;9:386-389.
ABSTRACT  

An Archival Study of Depression Before and After Age 55
Wesner and Winokur
J Geriatr Psychiatry Neurol 1988;1:220-225.
ABSTRACT  

The Social Environment and Psychopathology
Monroe
Journal of Social and Personal Relationships 1988;5:347-366.
ABSTRACT  

The Validity of Four Definitions of Endogenous Depression: II. Clinical, Demographic, Familial, and Psychosocial Correlates
Zimmerman et al.
Arch Gen Psychiatry 1986;43:234-244.
ABSTRACT  

Situational and Neurotic-Reactive Depression
Glass
Arch Gen Psychiatry 1985;42:1126-1127.
ABSTRACT