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IV. The Chestnut Lodge Follow-up Study

Thomas H. McGlashan, MD

Arch Gen Psychiatry. 1986;43(2):167-176.

Abstract
• Predictors of long-term outcome were identified among a sample (n=163) of largely chronic DSM-III schizophrenic patients (80% ill for more than two years) from the Chestnut Lodge follow-up study using three methods of analysis (correlation, multiple regression, and discriminant function). Predictors accounted for approximately one third of the outcome variance across six outcome dimensions. The following variables regularly (ie, individually and as components in multivariate equations) predicted better global outcome: less family history of schizophrenia, better premorbid instrumental functioning (interests and skills), more affective signs and symptoms (especially depression) in the manifest psychopathology, and absence of psychotic assaultiveness.

Author Affiliations
From Chestnut Lodge, Rockville, Md.

Footnotes
Accepted for publication Aug 21, 1984.

Read in part at the annual meeting of the American Psychiatric Association, Los Angeles, May 10, 1984.

Reprint requests to Chestnut Lodge, 500 W Montgomery Ave, Rockville, MD 20850 (Dr McGlashan).

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