Schizotypal personality disorder. Chestnut Lodge follow-up study: VI. Long-term follow-up perspectives
T. H. McGlashan
This study reports the first long-term follow-up of patients with
schizotypal personality disorder (SPD) as defined by DSM-III. Patients with
the pure syndrome (SPD, n = 10) were compared with patients with
schizophrenia (S, n = 53) and borderline personality disorder (BPD, n =
81). Three "mixed" cohorts (S/SPD, n = 61; S/SPD/BPD, n = 30; SPD/BPD, n =
18) were added to investigate the effect of schizotypal disorder on the
longitudinal course of comparison groups. Schizotypal personality disorder
proved to be common in the Chestnut Lodge follow-up study patients,
although it was rare as a pure syndrome. From the perspective of follow-up,
SPD appeared related to S but not to BPD. The mixed axis II borderline
syndrome (SPD/BPD) had a long-term profile closer to BPD than to SPD, and
adding SPD to S appeared (unexpectedly) to enhance outcome.
