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Chestnut Lodge Follow-up Study: VI. Long-term Follow-up Perspectives

Thomas H. McGlashan, MD

Arch Gen Psychiatry. 1986;43(4):329-334.

Abstract
• This study reports the first long-term follow-up of patients with schizotypal personality disorder (SPD) as defined by DSM-III. Patients with the pure syndrome (SPD, n =10) were compared with patients with schizophrenia (S, n=53) and borderline personality disorder (BPD, n = 81). Three "mixed" cohorts (S/SPD, n =61; S/SPD/BPD, n=30; SPD/BPD, n =18) were added to investigate the effect of schizotypal disorder on the longitudinal course of comparison groups. Schizotypal personality disorder proved to be common in the Chestnut Lodge follow-up study patients, although it was rare as a pure syndrome. From the perspective of follow-up, SPD appeared related to S but not to BPD. The mixed axis II borderline syndrome (SPD/BPD) had a long-term profile closer to BPD than to SPD, and adding SPD to S appeared (unexpectedly) to enhance outcome.

Author Affiliations
From Chestnut Lodge, Rockville, Md.

Footnotes
Accepted for publication Dec 17, 1984.

Reprint requests to Chestnut Lodge, 500 W Montgomery Ave, Rockville, MD 20850 (Dr McGlashan).

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