This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Mark Zimmerman; William Coryell, MD

Arch Gen Psychiatry. 1988;45(8):738-740.

Abstract
• Six hundred thirteen first-degree relatives of schizophrenics, depressives, and normal controls were interviewed with the Diagnostic Interview Schedule (DIS) and completed the Inventory to Diagnose Depression (IDD), a self-report scale to diagnose major depressive disorder (MDD). The current point prevalence of MDD was nearly identical according to the two measures (DIS, 2.8%; IDD, 2.6%). Diagnostic concordance varied according to the interval between the evaluations. When the two measures were completed within two days of each other the agreement was as high as can be expected between two instruments with less than perfect reliability. We used a family study approach to examine validity and found that both the DIS and IDD cases of depression were two to three times more frequent in the relatives of depressed patients than the relatives of schizophrenics and controls.

Author Affiliations
From the Department of Psychiatry, University of Iowa, Iowa City.

Footnotes
Accepted for publication Nov 6, 1987.

Reprint requests to Department of Psychiatry, University of Iowa School of Medicine, 500 Newton Rd, Iowa City, IA 52242 (Mr Zimmerman).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Depressive Symptoms and Mortality among Persons with and without Diabetes
Zhang et al.
Am J Epidemiol 2005;161:652-660.
ABSTRACT | FULL TEXT  

Changes in Lymphocyte Subsets in Depressed HIV-Infected Patients Without Antiretroviral Therapy
Alciati et al.
Psychosomatics 2001;42:247-251.
ABSTRACT | FULL TEXT  

Psychiatric Screening in Geriatric Primary Care: Should It Be for Depression Alone?
Lish et al.
J Geriatr Psychiatry Neurol 1995;8:141-153.
ABSTRACT  

Minor Depression and Functional Impairment
Jaffe et al.
Arch Fam Med 1994;3:1081-1086.
ABSTRACT  

A Pilot Swedish Twin Study of Affective Illness, Including Hospital- and Population-Ascertained Subsamples
Kendler et al.
Arch Gen Psychiatry 1993;50:699-706.
ABSTRACT  

A Family Study of Obsessive-Compulsive Disorder
Black et al.
Arch Gen Psychiatry 1992;49:362-368.
ABSTRACT  

Environmental Illness: A Controlled Study of 26 Subjects With '20th Century Disease'
Black et al.
JAMA 1990;264:3166-3170.
ABSTRACT