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Matti Virkkunen, MD; Judith De Jong, PhD; John Bartko, PhD; Markku Linnoila, MD, PhD

Arch Gen Psychiatry. 1989;46(7):604-606.

Abstract
• Psychobiological data on 58 violent offenders and impulsive fire setters were analyzed for associations with history of suicide attempts. Subjects with a history of suicide attempts serious enough to require an admission to a medical facility had significantly lower mean cerebrospinal fluid 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol concentrations than subjects who had not made such attempts. A linear discriminant function analysis based on psychobiological and behavioral variables correctly classified 79% of the subjects according to the suicide attempt history positive and negative outcomes.

Author Affiliations
From the Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism (Drs Virkunnen, De Jong, Bartko, and Linnoila), Division of Biometry and Applied Sciences, Intramural Research Program, National Institute of Mental Health (Dr Bartko), Bethesda, Md; and Department of Psychiatry, University of Helsinki (Finland) (Dr Virkkunen).

Footnotes
Accepted for publication October 28, 1988.

Reprint requests to National Institute on Alcohol Abuse and Alcoholism, Bldg 10, Room 3B19, 9000 Rockville Pike, Bethesda, MD 20892 (Dr Linnoila).

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