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Markku Linnoila, MD, PhD; Judith De Jong, PhD; Matti Virkkunen, MD

Arch Gen Psychiatry. 1989;46(7):613-616.

Abstract
• Fifty-six of 58 violent offenders and impulsive fire setters fulfilled the DSM-III criteria for alcohol abuse. Information necessary for evaluation of family history of alcoholism was obtained on 54 subjects. Forty-four of the 54 subjects had first- or second-degree blood relatives with alcoholism. Thirty-five had alcoholic fathers. Subjects with alcoholic fathers had a lower mean cerebrospinal fluid 5-hydroxyindoleacetic acid concentration and were more often impulsive than subjects without alcoholic fathers.

Author Affiliations
From the Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Md (Drs Linnoila and De Jong); and Department of Psychiatry, University of Helsinki (Finland) (Dr Virkkunen).

Footnotes
Accepted for publication October 28, 1988.

Reprint requests to LCS, DICBR, NIAAA, Bldg 10, Room 3B19, 9000 Rockville Pike, Bethesda, MD 20892 (Dr Linnoila).

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