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  Vol. 47 No. 11, November 1990 TABLE OF CONTENTS
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Pronounced Reduction of Total Neuron Number in Mediodorsal Thalamic Nucleus and Nucleus Accumbens in Schizophrenics

Bente Pakkenberg, MD

Arch Gen Psychiatry. 1990;47(11):1023-1028.


Abstract

• Using a new and unbiased stereological technique, the total numbers of neuron and glial cells in the mediodorsal thalamic nucleus and the nucleus accumbens were found to be significantly reduced in schizophrenic patients compared with controls. The total neuron and glial cell number in the ventral pallidum and in the basolateral nucleus of amygdala did not differ in the two groups.



Author Affiliations

From the Neurological Research Laboratory, Hvidovre Hospital, Copenhagen, Denmark.


Footnotes

Accepted for publication December 1, 1989.

Read in part before the Seventh European Winter Conference on Brain Research, Val Thorens, France, March 21, 1987, and at the 27th meeting of the American College of Neuropsychopharmacology, Puerto Rico, December 16, 1988.

Reprint requests to Neurological Research Laboratory, Pav 4, Hvidovre Hospital, Kettegaards Alle 30, 2650 Hvidovre, Copenhagen, Denmark (Dr Pakkenberg).



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