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Graham J. Emslie, MD; A. John Rush, MD; Warren A. Weinberg, MD; Jeanne W. Rintelmann; Howard P. Roffwarg, MD

Arch Gen Psychiatry. 1990;47(2):119-124.

Abstract
• A substantial body of research in adults has established that certain sleep polysomnographic abnormalities are commonly found in depressed patients, including sleep continuity disturbances, reduced slow-wave sleep, shortened rapid eye movement (REM) latency, and increased REM density. To date, these abnormalities have not been documented in depressed children compared with age-matched controls. Three consecutive nights of polysomnographic recordings were obtained in 25 hospitalized depressed children and 20 age-matched healthy controls. The depressed patients had reduced REM latencies. The shortest single-night REM latency of each individual was the most sensitive discriminating value between depressed subjects and controls. The influence of different scoring criteria in distinguishing depressed children from healthy children is discussed. In addition, depressed children had an increased sleep latency and increased REM time but did not have stage 4 differences.

Author Affiliations
From the Departments of Psychiatry (Drs Emslie, Rush, and Roffwarg and Ms Rintelmann) and Neurology (Dr Weinberg), University of Texas Southwestern Medical Center at Dallas.

Footnotes
Accepted for publication May 26, 1989.

Presented as a poster exhibit at the annual meeting of the American Academy of Child and Adolescent Psychiatry, Washington, DC, October 24, 1987.

Reprint requests to Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75235 (Dr Emslie).

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