You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 49 No. 8, August 1992 TABLE OF CONTENTS
  Archives
  •  Online Features
  ORIGINAL ARTICLES
 This Article
 •References
 •Full text PDF
 • Reply to article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit Add to Technorati Add to Twitter What's this?

Types of Alcoholics, I

Evidence for an Empirically Derived Typology Based on Indicators of Vulnerability and Severity

Thomas F. Babor, PhD; Michael Hofmann, PhD; Frances K. DelBoca, PhD; Victor Hesselbrock, PhD; Roger E. Meyer, MD; Zelig S. Dolinsky, PhD; Bruce Rounsaville, MD

Arch Gen Psychiatry. 1992;49(8):599-608.


Abstract

• An empirical clustering technique was applied to data obtained from 321 male and female alcoholics to identify homogeneous subtypes having discriminative and predictive validity. The clustering solution identified two "types" of alcoholics who differed consistently across 17 defining characteristics in the male and female samples. One group, designated type A alcoholics, is characterized by later onset, fewer childhood risk factors, less severe dependence, fewer alcohol-related problems, and less psychopathological dysfunction. The other group, termed type B alcoholics, is characterized by childhood risk factors, familial alcoholism, early onset of alcohol-related problems, greater severity of dependence, polydrug use, a more chronic treatment history (despite their younger age), greater psychopathological dysfunction, and more life stress. The two types also differed with respect to treatment outcome assessed prospectively at 12 and 36 months. The results are consistent with historical and contemporary typological theories that have postulated similar subgroups of alcoholics. The findings suggest that an empirically derived, multivariate typology of alcoholism has theoretical implications for explaining the heterogeneity among alcoholics and may provide a useful basis for predicting course and estimating treatment response.



Author Affiliations

From the Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington (Drs Babor, DelBoca, Hesselbrock, Meyer, and Dolinsky); the Connecticut Commission on Hospital and Health Care, Hartford (Dr Hofmann), and the Department of Psychiatry, Yale Medical School, New Haven, Conn (Dr Rounsaville).


Footnotes

Accepted for publication July 24, 1991.

Reprint requests to Department of Psychiatry, University of Connecticut Health Center, Farmington, CT 06030 (Dr Babor).



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Impact of Tryptophan Metabolism on the Vulnerability to Alcohol-Related Blackouts and Violent Impulsive Behaviours
Vignau et al.
Alcohol Alcohol 2009;0:agp044v1-agp044.
ABSTRACT | FULL TEXT  

The Alcoholic Phenotypes among Different Multidimensional Typologies: Similarities and Their Classification Procedures
Pombo and Lesch
Alcohol Alcohol 2009;44:46-54.
ABSTRACT | FULL TEXT  

Identifying Heterogeneity Among Injection Drug Users: A Cluster Analysis Approach
Shaw et al.
AJPH 2008;98:1430-1437.
ABSTRACT | FULL TEXT  

Neurobiology and Treatment in Alcoholism--Recent Findings Regarding Lesch's Typology of Alcohol Dependence
Hillemacher and Bleich
Alcohol Alcohol 2008;0:agn016v1-agn016.
ABSTRACT | FULL TEXT  

Invited Commentary * Serotonin transporter (SERT) brain density and neurobiological cloninger subtypes model: a lesson by human autoradiography studies
Leggio and Addolorato
Alcohol Alcohol 2008;43:148-150.
ABSTRACT | FULL TEXT  

ALCOHOLISM AND HOMICIDE WITH RESPECT TO THE CLASSIFICATION SYSTEMS OF LESCH AND CLONINGER
REULBACH et al.
Alcohol Alcohol 2007;42:103-107.
ABSTRACT | FULL TEXT  

Alcohol consumption and the use of antidepressants
Graham and Massak
CMAJ 2007;176:633-637.
ABSTRACT | FULL TEXT  

Conduct Disorder and Antisocial Personality Disorder in Persons With Severe Psychiatric and Substance Use Disorders
Mueser et al.
Schizophr Bull 2006;32:626-636.
ABSTRACT | FULL TEXT  

The Genetics of Addictions: Uncovering the Genes
Goldman et al.
Focus 2006;4:401.
ABSTRACT | FULL TEXT  

Alcohol, drugs, and attention-deficit/ hyperactivity disorder: a model for the study of addictions in youth
Wilens and Biederman
J Psychopharmacol 2006;20:580-588.
ABSTRACT  

NETER ALCOHOLIC TYPOLOGY (NAT)
CARDOSO et al.
Alcohol Alcohol 2006;41:133-139.
ABSTRACT | FULL TEXT  

A Genome-Wide Search for Quantitative Trait Loci That Influence Antisocial Drug Dependence in Adolescence
Stallings et al.
Arch Gen Psychiatry 2005;62:1042-1051.
ABSTRACT | FULL TEXT  

Anticraving Medications for Relapse Prevention: A Possible New Class of Psychoactive Medications
O'Brien
Am. J. Psychiatry 2005;162:1423-1431.
ABSTRACT | FULL TEXT  

CLINICAL PREDICTORS OF RESPONSE TO NALTREXONE IN ALCOHOLIC PATIENTS: WHO BENEFITS MOST FROM TREATMENT WITH NALTREXONE?
RUBIO et al.
Alcohol Alcohol 2005;40:227-233.
ABSTRACT | FULL TEXT  

Haplotype-Based Localization of an Alcohol Dependence Gene to the 5q34 {gamma}-Aminobutyric Acid Type A Gene Cluster
Radel et al.
Arch Gen Psychiatry 2005;62:47-55.
ABSTRACT | FULL TEXT  

Identifying Subtypes of Civil Psychiatric Patients at High Risk for Violence
Skeem et al.
Criminal Justice and Behavior 2004;31:392-437.
ABSTRACT  

PHARMACOTHERAPEUTIC TRIALS IN ADOLESCENT ALCOHOL USE DISORDERS: OPPORTUNITIES AND CHALLENGES
Dawes and Johnson
Alcohol Alcohol 2004;39:166-177.
ABSTRACT | FULL TEXT  

Perceptions of the Family Environment and Youth Behaviors: Alcohol-Abusing Runaway Adolescents and Their Primary Caretakers.
Slesnick and Prestopnik
The Family Journal 2004;12:243-253.
ABSTRACT  

CORRELATES OF EXTERNALIZING SYMPTOMS IN CHILDREN FROM FAMILIES OF ALCOHOLICS AND CONTROLS
Schuckit et al.
Alcohol Alcohol 2003;38:559-567.
ABSTRACT | FULL TEXT  

Is ADHD a Risk Factor for Psychoactive Substance Use Disorders? Finding From a Four-Year Prospective Follow-Up Study
Biederman et al.
Focus 2003;1:196-204.
ABSTRACT | FULL TEXT  

NO ASSOCIATION BETWEEN A POLYMORPHISM IN THE PROMOTER REGION OF THE MAOA GENE WITH ANTISOCIAL PERSONALITY TRAITS IN ALCOHOLICS
Koller et al.
Alcohol Alcohol 2003;38:31-34.
ABSTRACT | FULL TEXT  

HARMFUL DRINKING IN MILITARY VETERANS WITH POST-TRAUMATIC STRESS DISORDER: ASSOCIATION WITH THE D2 DOPAMINE RECEPTOR A1 ALLELE
Young et al.
Alcohol Alcohol 2002;37:451-456.
ABSTRACT | FULL TEXT  

THE RELATIONSHIP BETWEEN THE FAMILY DENSITY OF ALCOHOLISM AND EXTERNALIZING SYMPTOMS AMONG 146 CHILDREN
Barnow et al.
Alcohol Alcohol 2002;37:383-387.
ABSTRACT | FULL TEXT  

Role of Steroids in Sex Differences in Morphine-Induced Analgesia: Activational and Organizational Effects
Cicero et al.
J. Pharmacol. Exp. Ther. 2002;300:695-701.
ABSTRACT | FULL TEXT  

FEMALE ALCOHOLISM: DIFFERENCES BETWEEN FEMALE ALCOHOLICS WITH AND WITHOUT A HISTORY OF ADDITIONAL SUBSTANCE MISUSE
Hallman et al.
Alcohol Alcohol 2001;36:564-571.
ABSTRACT | FULL TEXT  

Substance Use, Substance Abuse, and LD Among Adolescents with a Childhood History of ADHD
Molina and Pelham
J Learn Disabil 2001;34:333-342.
ABSTRACT  

Sweet liking and family history of alcoholism in hospitalized alcoholic and non-alcoholic patients
Kampov-Polevoy et al.
Alcohol Alcohol 2001;36:165-170.
ABSTRACT | FULL TEXT  

Medications for Alcohol Dependence--New Vistas
Kranzler
JAMA 2000;284:1016-1017.
FULL TEXT  

RISK FACTORS FOR ALCOHOL DEPENDENCE: A CASE-CONTROL STUDY
Poikolainen
Alcohol Alcohol 2000;35:190-196.
ABSTRACT | FULL TEXT  

Pharmacotherapy of Attention-deficit/Hyperactivity Disorder Reduces Risk for Substance Use Disorder
Biederman et al.
Pediatrics 1999;104:20e-20.
ABSTRACT | FULL TEXT  

ASSOCIATION BETWEEN PREFERENCE FOR SWEETS AND EXCESSIVE ALCOHOL INTAKE: A REVIEW OF ANIMAL AND HUMAN STUDIES
Kampov-Polevoy et al.
Alcohol Alcohol 1999;34:386-395.
ABSTRACT | FULL TEXT  

Genetic and Environmental Contributions to Alcohol Abuse and Dependence in a Population-Based Sample of Male Twins
Prescott and Kendler
Am. J. Psychiatry 1999;156:34-40.
ABSTRACT | FULL TEXT  

Linkage of Antisocial Alcoholism to the Serotonin 5-HT1B Receptor Gene in 2 Populations
Lappalainen et al.
Arch Gen Psychiatry 1998;55:989-994.
ABSTRACT | FULL TEXT  

Replication of the Stockholm Adoption Study of Alcoholism: Confirmatory Cross-Fostering Analysis
Sigvardsson et al.
Arch Gen Psychiatry 1996;53:681-687.
ABSTRACT  

Alcohol Treatment and Health Care System Reform
McCrady and Langenbucher
Arch Gen Psychiatry 1996;53:737-746.
ABSTRACT  

Specificity of Ethanollike Effects Elicited by Serotonergic and Noradrenergic Mechanisms
Krystal et al.
Arch Gen Psychiatry 1994;51:898-911.
ABSTRACT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1992 American Medical Association. All Rights Reserved.