This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (27)  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in this journal  Topic Collections  • Bipolar Disorder  • Alert me on articles by topic  Social Bookmarking   What's this?

Arch Gen Psychiatry. 1998;55:23-25.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

SINCE THE advent of the psychopharmacological revolution, manic-depressive illness has been the flagship for modern psychiatric research, a paradigm that inspired and shaped many other areas of research. Today, through the accumulation of knowledge of this illness and its treatment, it constitutes one of the extraordinary success stories of modern biochemical science. Almost 30 years ago, Robins and Guze¹ outlined 4 criteria for diagnostic validity in psychiatric disorders: clinical phenomenology, genetics, course, and treatment response. In each of these areas, our accumulated knowledge about manic-depressive illness is indeed impressive. But we face a paradox. Despite all we know, the illness too often remains unrecognized or misdiagnosed and inappropriately or ineffectively treated. The criteria of Robins and Guze encompass the 4 articles^2-5 in this issue about the illness and can serve as springboards to comment on the contemporary understanding of this fascinating and challenging illness.

CLINICAL PHENOMENOLOGY

Clinical phenomenology is the buttress that . . . [Full Text of this Article]

DIRECTIONS FOR GENETIC RESEARCH

OUTCOME

PATTERNS OF MOOD-STABILIZING TREATMENT

CONCLUSIONS


CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLES

A Factor Analysis of the Signs and Symptoms of Mania
Frederick Cassidy, Kara Forest, Elizabeth Murry, and Bernard J. Carroll
Arch Gen Psychiatry. 1998;55(1):27-32.
ABSTRACT | FULL TEXT  

Association Between the Tryptophan Hydroxylase Gene and Manic-depressive Illness
Frank Bellivier, Marion Leboyer, Philippe Courtet, Catherine Buresi, Béatrice Beaufils, Danielle Samolyk, Jean-François Allilaire, Josue Feingold, Jacques Mallet, and Alain Malafosse
Arch Gen Psychiatry. 1998;55(1):33-37.
ABSTRACT | FULL TEXT  

Cognitive Impairment in Euthymic Bipolar Patients With and Without Prior Alcohol Dependence: A Preliminary Study
Wilfred G. van Gorp, Lori Altshuler, David C. Theberge, Jeffery Wilkins, and Wilfrid Dixon
Arch Gen Psychiatry. 1998;55(1):41-46.
ABSTRACT | FULL TEXT  

Twelve-Month Outcome After a First Hospitalization for Affective Psychosis
Stephen M. Strakowski, Paul E. Keck, Jr, Susan L. McElroy, Scott A. West, Kenji W. Sax, John M. Hawkins, Geri F. Kmetz, Vidya H. Upadhyaya, Karen C. Tugrul, and Michelle L. Bourne
Arch Gen Psychiatry. 1998;55(1):49-55.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Is valproate promising in cardiac fatal arrhythmias? Comparison of P- and Q-wave dispersion in bipolar affective patients on valproate or lithium-valproate maintenance therapy with healthy controls
E et al.
J Psychopharmacol 2009;23:328-333.
ABSTRACT  

Effects of acute tryptophan depletion on mood and suicidal ideation in bipolar patients symptomatically stable on lithium
HUGHES et al.
Br. J. Psychiatry 2000;177:447-451.
ABSTRACT | FULL TEXT