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Several laboratories using functional neuroimaging techniques have recently reported that patients with posttraumatic stress disorder (PTSD) have increased blood flow or metabolism in right limbic, paralimbic, and frontal cortical structures when recalling the traumatic event associated with their symptoms.^1-4 This observation is consistent with several studies implicating preferential right hemispheric involvement in the experience of unpleasant emotion.^5-10 Taken together, these findings suggest that right limbic and paralimbic structures are intimately involved with the emotional symptoms associated with traumatic memories,¹¹ and could potentially be the target of neurobiological treatment strategies.

One potential method for interfering with neuronal circuitry associated with traumatic memories is repetitive transcranial magnetic stimulation (RTMS). This technique, which involves placement of a water-cooled electromagnet with a figure-eight coil on the scalp and rapidly turning the magnetic flux on and off, permits noninvasive, relatively focal stimulation of the cerebral cortex. The effect of magnetic stimulation varies, depending on the . . . [Full Text of this Article]

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