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Arch Gen Psychiatry. 2000;57:540-542.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

SOME MEDICAL ethics questions are age-old and may be best understood through careful conceptual analysis and reflection. Some are not. Indeed, some ethics issues have emerged primarily as empirical questions of tremendous significance within modern biomedical science and clinical care. The current controversy surrounding the ethical acceptability of research involving people with mental illness serves as an important illustration of the way in which data may help to resolve contemporary moral questions. For instance, one argument against the participation of mentally ill individuals in research is the presumption that they are unable to make this choice freely and in a manner that appropriately weighs the personal risks of participation in relation to the potential benefits for themselves, science, and society.¹ Recent data on the values, motivations, and risk assessments expressed by psychiatric patients may radically challenge these beliefs regarding their capacity for autonomy and altruism in the context of clinical . . . [Full Text of this Article]

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