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  Vol. 57 No. 8, August 2000 TABLE OF CONTENTS
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A Mind That Tics

Arch Gen Psychiatry. 2000;57:753.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

NEUROLOGY'S dictum—localize the lesion—is being applied with vigor to neuropsychiatric disorders. A century ago, Hughlings Jackson admonished us to avoid the pitfall of equating the deficits after lesions with the functions of the area destroyed. Similarly, Walsh1 rejected the theory of cerebellar "braking" to explain dysmetria after cerebellar lesions. The cerebellum was considered to inhibit overshooting and undershooting. He provided a lovely metaphor for misunderstanding brain function: that of an automobile transmission with a gear tooth knocked off, causing a "clunk" when the drive shaft turns slowly and a vibration at faster speeds. One might conclude that the gear tooth prevents clunks and vibrations, supported by their resolution after the tooth is replaced. The gear teeth, however, transmit power from the drive to the shaft.

The modern era of positron emission tomography, functional magnetic resonance imaging, and other functional imaging studies engender different cautions. The word "functional" before "imaging" and . . . [Full Text of this Article]



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A Functional Neuroanatomy of Tics in Tourette Syndrome
Emily Stern, David A. Silbersweig, Kit-Yun Chee, Andrew Holmes, Mary M. Robertson, Michael Trimble, Christopher D. Frith, Richard S. J. Frackowiak, and Raymond J. Dolan
Arch Gen Psychiatry. 2000;57(8):741-748.
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