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Lithium: An Orphan Drug
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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I was pleased to read the analysis by Baldessarini and Tondo1 indicating that, contrary to some reports, lithium
has not lost its efficacy as a treatment for bipolar disorder in recent years.
Certainly their findings are in accord with my own clinical experience that
lithium is effective and well tolerated, especially at moderate serum lithium
concentrations, as they note in their report.
One factor that may be responsible for lithium's fall from grace among
clinicians and patients is its status as an "orphan" or "poor relative." Since
lithium is cheap and unpatented, no wealthy drug company has any interest
in demonstrating its merits as a mood stabilizer. There are no lavishly catered
all-star symposia at major psychiatric meetings to sing the praises of this
humble salt. And when did you last see a pen, notepad, calendar, or trinket
with "Lithium" embossed on it? Finally, lithium is regarded as old news . . . [Full Text of this Article]
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