This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Harlow et al¹ recently published data from a study describing prevalence and predictors of depression in older premenopausal women. The study describes a significant rate (22.4%) of current depressive symptoms (defined as Center for Epidemiologic Studies Depression Scale [CES-D]² score >16) in a cross-sectional population-based study. It also describes a significant association between past or current depression and a higher risk for depressive symptoms and premenstrual complaints, particularly among women with significant premenstrual functioning impairment.

In a recent study,^{3, 4} we noted a high prevalence (49.5%) of psychiatric morbidity (Self-Rating Questionnaire score [SRQ-20]⁵ >7) among 101 endocrinologically confirmed perimenopausal women attending a menopause clinic (age, 40-58 years; menstrual irregularity, >6 months; amenorrhea, <1 year; follicle-stimulating hormone levels, >20 IU/L). In addition, all women experiencing significant psychiatric symptoms were further assessed with the Mood Module from the Primary Care Evaluation of Mental Disorders (PRIME-MD) questionnaire⁶ to investigate depressive disorders according to DSM-IV⁷ . . . [Full Text of this Article]

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Premenstrual Symptoms and Perimenopausal Depression
Richards et al.
Am. J. Psychiatry 2006;163:133-137.
ABSTRACT | FULL TEXT  

A Longitudinal Evaluation of the Relationship Between Reproductive Status and Mood in Perimenopausal Women
Schmidt et al.
Am. J. Psychiatry 2004;161:2238-2244.
ABSTRACT | FULL TEXT  

Efficacy of Estradiol for the Treatment of Depressive Disorders in Perimenopausal Women: A Double-blind, Randomized, Placebo-Controlled Trial
de Novaes Soares et al.
Arch Gen Psychiatry 2001;58:529-534.
ABSTRACT | FULL TEXT